OLAPTESED PEGOL
Olaptesed pegol is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against stromal cell-derived factor 1.
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Commercial
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic disease | D002908 | — | — | 2 | 1 | — | — | — | 3 |
| Anemia | D000740 | HP_0001903 | D64.9 | 2 | 2 | — | — | — | 3 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.9 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Endotoxemia | D019446 | — | — | 1 | — | — | — | — | 1 |
| Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | OLAPTESED PEGOL |
| INN | olaptesed pegol |
| Description | Olaptesed pegol is an unknown pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against stromal cell-derived factor 1. |
| Classification | Unknown |
| Drug class | aptamers, classical and mirror; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4594485 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | MTM792B442 (ChemIDplus, GSRS) |
Target
Agency Approved
CXCL12
CXCL12
Organism
Homo sapiens
Gene name
CXCL12
Gene synonyms
SDF1, SDF1A, SDF1B
NCBI Gene ID
Protein name
stromal cell-derived factor 1
Protein synonyms
C-X-C motif chemokine 12, chemokine (C-X-C motif) ligand 12, hIRH, Intercrine reduced in hepatomas, IRH, PBSF, Pre-B cell growth-stimulating factor
Uniprot ID
Mouse ortholog
Cxcl12 (20315)
stromal cell-derived factor 1 (Q543V6)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
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Additional graphs summarizing 49 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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